The main aim of the HistoInformatics initiative has been to develop a market leading software/hardware system, the HistoInformatics platform, capable of high-speed sampling and quantitative analysis of large batches of biomedical microscopic images. Three partners from university and industry have been involved.

This project has in the period 2007-2010 been supported by a grant of 8 mill. DKK (more than 1 mill. Euro) from the Programme Comission on Nanoscience, Biotechnology an IT under the Danish Council for Strategic Research.

Part of the research of the HistoInformatics project has been continued in the new Centre of Excellence Centre for Stochastic Geometry and advanced Bioimaging, fundet by the Villum Foundation.

Two pyramidal neurons in the cortex in a slice of a mouse brain visualized with a green-fluroecsent dye.Cortex of a brain slice in a mouse model of epilepsy. All cells have been stained with blue-fluorecsent dye. Specific neurons in cortex have been stained with green and red fluorescent dyes, discriminating between inhibitory and excitatory cells, respectively.Tissue section from the inner ear (balance organ) of a waltzing guinea pig. Cell nuclei and nerve afferents are visualized with blue and green fluorescent dyes, respectively, with yellow and red colors highlighting specific proteins present in (e.g.) the hair bundles on the cell surface layer.

Figure 1: Two pyramidal neurons in the cortex in a slice of a mouse brain visualized with a green-fluroecsent dye.
Figure 2: Cortex of a brain slice in a mouse model of epilepsy. All cells have been stained with blue-fluorecsent dye. Specific neurons in cortex have been stained with green and red fluorescent dyes, discriminating between inhibitory and excitatory cells, respectively.
Figure 3: Tissue section from the inner ear (balance organ) of a waltzing guinea pig. Cell nuclei and nerve afferents are visualized with blue and green fluorescent dyes, respectively, with yellow and red colors highlighting specific proteins present in (e.g.) the hair bundles on the cell surface layer.

Innovative Features



Collaborating Partners